Fresh frozen plasma and neonatal sepsis.

Effect of fresh frozen plasma and gammaglobulin on humoral immunity in neonatal sepsis.

Fresh frozen plasma and intravenous immunoglobulin are used as prophylaxis against, and for the treatment of, neonatal infection. It is assumed that any beneficial effect is mediated through the humoral immune factors contained in each preparation. The effect of fresh frozen plasma and intravenous immunoglobulin on humoral immune markers (immunoglobulins and IgG subclasses, complement component...

Fresh frozen plasma induced thrombocytopenia

Transfusions of blood products are common in medical practice and can be lifesaving in certain situations. Potentially life threatening reactions could occur and physicians should be alerted. Here we describe a case of thrombocytopenia that was induced by transfusion of fresh frozen plasma (FFP). A 52 years old male presented to the emergency department after two episodes of hematochezia that r...

Avoiding the misuse of fresh frozen plasma.

Fresh Frozen Plasma Use in a Neonatal Unit in South Africa.

BACKGROUND Despite limited evidence, fresh frozen plasma (FFP) transfusions are a relatively common neonatal procedure. OBJECTIVES Quantify FFP usage in our unit; determine indications for transfusions and compliance with published guidelines. METHODS Data were retrospectively collected on infants who received FFP from January 2009 to December 2013. RESULTS Admissions totalled 10 912 infa...

APROTININ: EFFECTS ON BLOOD LOSS AND FRESH FROZEN PLASMA REQUIREMENT IN CARDIAC OPERATIONS

 ABSTRACT Background: Aprotinin has been used increasingly to reduce postoperative blood loss in open-heart operations due to the potentialities for complications and high cost, it would seem reasonable to use aprotinin more selectively in small doses in the prime solution of the pump. Methods: We prospectively studied the effect of preoperative low dose aprotinin [2 million units (230mg)] on b...